Illumina NextSeq 1000 is versatile and is used in applications such as whole-genome sequencing, exome sequencing, RNA sequencing, and targeted resequencing. It supports a range of research fields including genomics, transcriptomics, and epigenomics, making it suitable for large-scale studies and comprehensive analyses.

Illumina MiniSeq is geared towards applications such as targeted resequencing, small RNA sequencing, and targeted gene expression analysis. It is ideal for clinical research, small-scale genomics projects, and labs that require high-quality sequencing with lower throughput and cost.

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The Lenovo Server Tower 550, recently installed at the college, has an Intel Xeon Silver 4210 processor featuring 10 cores at 2.2GHz and 85 W power. It has a 3.5" SATA/SAS storage system with a 2 × 4-Bay Backplane and Think System RAID 530-8i PCIe for efficient data management. The server was powered by a 32GB TruDDR4 2933 MHz RDIMM and supported by an NVIDIA T1000 4GB GDDR6 graphics card. Additional features include Lenovo X Clarity Enterprise, dual 1G ports, 750 W dual PSUs, and 24 × 7 4-h response services for reliable performance.

This server is used to process and analyze the NGS output data

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The Seahorse instrument is a specialized tool designed to study cellular bioenergetics in real-time. It measures cellular oxygen consumption rate (OCR) and extracellular acidification rate (ECAR), which are key indicators of cellular respiration and glycolysis, respectively. ?It is widely used in cellular biology and metabolic research. The ability to perform real-time, non-invasive measurements allows researchers to gain a comprehensive understanding of cellular bioenergetics and metabolic pathways. For example, mitochondrial function, glycolytic activity, cellular stress response to chemicals, assessment of the bioenergetic profiles of different cell types, and the influence of cellular metabolism on cell function and response.

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Beckman Coulter CytoFLEX is a high-performance flow cytometer designed for multi-parameter analysis with exceptional sensitivity and resolution. It features a customizable configuration with up to 21 parameters, allowing for detailed cellular and particle analysis. This system utilizes advanced optical technology to enhance signal detection and minimize background noise. CytoFLEXs include immunophenotyping, cell cycle analysis, and apoptosis studies. It is also used in hematology, oncology, and immunology research, providing critical insights into cellular functions and molecular interactions. CytoFLEX is suitable for both basic and advanced research, offering the flexibility to adapt to various experimental needs.

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An individually ventilated cage (IVC) system provides a controlled environment for laboratory animals with individual ventilation in each cage. It ensures optimal conditions by controlling airflow, temperature, and humidity while reducing cross-contamination between cages. Nude mice in an individually ventilated cage (IVC) system are used for diverse studies such as cancer research, immunology, and drug development owing to their compromised immune systems. The IVC system provides controlled environmental conditions that are essential for accurate tumour growth, immune response analysis, and genetic modifications. It also supports research on transplantation and infectious diseases by minimizing cross-contamination and ensuring optimal conditions for obtaining reliable results. 365体育投注 in pharmacology, toxicology, and genetics, where precise environmental control is necessary. It is also used for high-maintenance animal studies and in environments requiring stringent pathogen control, supporting both breeding and experimental studies.

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The iBright Imaging System from Thermo Fisher is a cutting-edge platform for western blot analysis that offers high-resolution and quantitative imaging to accurately detect and analyze proteins. This enhances sensitivity and simplifies workflows, making protein detection more efficient. This device underscores its role in advancing the research capabilities.

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Confocal microscopy is a powerful imaging tool for visualizing and analyzing biological specimens with exceptional detail and precision. Providing high-resolution, three-dimensional images of biological specimens offer improved optical sectioning and reduced background noise compared to traditional wide-field microscopy. Used in biomedical research to visualize cellular organelles, membrane spatial and temporal patterns of gene expression, cell differentiation, tissue architecture, and liver cell imaging allows tracking dynamic cellular processes over time. FRET to investigate molecular interactions in proximity between fluorophore-labeled molecules.

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